fibronectin in reflux nephropathy is it a marker of reflux grade?

نویسندگان

nahid rahimzadeh pediatric transplantation and dialysis research center

mersedeh ghodsi

mina torkzaban labafi nejad hospital

چکیده

background and objective: vesicoureteral reflux (vur) is one of the most common urinary tract abnormalities in patients with urinary tract infection. nowadays noninvasive diagnostic methods are suggested to recognize vur and its severity. methods: we measured urinary and serum fibronectin in 51 children with vur. results: the mean serum fibronectin was 318.3±112.1 in children with low grade vur versus 356.1±189.9 in children with high grade vur (p>0.05). the mean urinary fibronectin was also 31.5±12.9 in low grade vur and 25.9±14.2 in high grade vur (p>0.05). thus we found no association between the severity of vur and the amount of fibronectin in serum and urine of patients. we also f found no relationship between dimercaptosuccinic acid (dmsa) changes at the acute phase of unitary tract infection (uti) and serum and urine fibronectin. conclusion: contrary to some previous studies, we showed the serum and urinary fibronectin cannot preclude the severity and grade of vur and hence it is not suitable surrogate marker for imaging techniques for vur diagnosis.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fibronectin in reflux nephropathy Is it a marker of reflux grade?

Background and Objective: Vesicoureteral reflux (VUR) is one of the most common urinary tract abnormalities in patients with urinary tract infection. Nowadays noninvasive diagnostic methods are suggested to recognize VUR and its severity. Methods: We measured urinary and serum fibronectin in 51 children with VUR. Results: The mean serum fibronectin was 318.3±112.1 in chi...

متن کامل

Diagnosis of Vesicoureteric Reflux and Reflux Nephropathy

FIGURE 8-12 International system of radiographic grading of vesicoureteral reflux (VUR). The severity of VUR is most frequently classified according to the International Grading System of Vesicoureteral Reflux, using a standardized technique for performance of voiding cystourethrography. The definitions of this system are illustrated in Figure 8-4 and are as follows. In grade I, reflux only int...

متن کامل

Reflux and Obstructive Nephropathy

Reflux nephropathy, or renal parenchymal scarring associated with vesicoureteral reflux (VUR), is an important cause of renal failure. Some studies have shown that in up to 10% of adults and 30% of children requiring renal replacement therapy for end-stage renal disease, reflux nephropathy is the cause of the renal failure. Reflux nephropathy is thought to result from the combination of VUR of ...

متن کامل

Radionuclide scans in reflux nephropathy

Early feeding difficulties in infants with a cleft palate are well documented' as is poor mother-infant bonding.2 For many years these infants have been fed with various makeshift modifications of a teat. Over the last year we have been using a new feeder specifically designed to overcome many of the problems of feeding such infants. The new 'Haberman' feeder consists of four components (see fi...

متن کامل

Vesicoureteral Reflux, Reflux Nephropathy, and End-Stage Renal Disease

OBJECTIVE To review the contribution of vesicoureteral reflux and reflux nephropathy to end-stage renal disease. DATA SOURCE Published research articles and publicly available registries. RESULTS Vesicoureteral reflux (VUR) is commonly identified in pediatric patients and can be associated with reflux nephropathy (RN), chronic kidney disease (CKD), and rarely end-stage renal disease (ESRD)....

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
مجله بین المللی کودکان و نوجوانان

جلد ۱، شماره ۱، صفحات ۱۰-۱۳

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023